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Postmenopausal women on the GLP 1 medication tirzepatide (Zepbound) for obesity lost more weight if they were also using menopause hormone therapy, a retrospective cohort study indicated. https: www.medpagetoday.com endocrinology menopause 119594 Castle Rock Contouring (@castlerockcontouring) Facebook Zepbound Plateau: Why Weight Loss Stalls and What to Do Next Shed Does tirzepatide affect your period? What to know about menstrual changes on a GLP 1 A recent post hoc analysis published in Obesity found tirzepatide vs. placebo was not associated with increased risk of depression symptoms. Rates of suicidal ideation and behavior were low and similar to
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.9 ★★★★★
Based on 1757 reviews
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Product Reviews
★★★★★ 5
Very durable and my Heeler's fave inside toy
Size: Large
My red Heeler loves these balls, second only to Tennis balls but she destroys those within minutes and they are outside only. This is her inside ball. She is hard on toys and has the strongest bite of any dog I've had (shepherds, collies, weimaraners, retrievers, Labs) yet these continue to last. She catches the ball, we play tug of war with it (she places it in hand hand and pulls only when I have a firm grip, she shakes it and flings it. The rubber outside even outlasts the water-bottle like plastic piece inside. Steps holds the ball with her foot and pulls on the rubber with her mouth, stretching it to sometimes twice its size. I pull while shes pulling. This thing gets abused daily and keeps on going. Its the most used toy and she brings it to me to play with every day. Each ball lasts about 6 months before the inside ball is toast and the outer rubber is finally starting to tear/break. which for me in an incredibly long time. If this ball is available to play, she wants it over all others. Shes NEVER gotten a piece off to actually swallow and that alone is worth the price.
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Reviewed in the United States on June 4, 2025
★★★★★ 4
Good for price
Size: Medium
Good product, wish it was a little more chew resistant
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Reviewed in the United States on April 29, 2026
★★★★★ 5
Dogs go for this ball every time
Size: Large, Size: Large
My Boston's and Rotti love this ball. I had to get two more. It's great for the Boston's because they can grasp it with the way it's made with the softer rubber. They love the crackle sound. It's just the right size and weight for smaller like the Boston Terrier and Rotti. Easy cleaning, rinses right off.
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Reviewed in the United States on May 13, 2026
★★★★★ 3
No more crackle
Size: Medium
The inside “crackle” part broke immediately. Still ok for playing with, outside is durable
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Reviewed in the United States on February 12, 2026
★★★★★ 5
It's a Hit a Our House!
Size: Large
My strong chewer is still ..... Well, going strong! He loves his new crackle ball.
He enjoys the new sound, the bounce back feeling in his jaws when chews.
Mom is happy that pup hasn't put a dent in the toy yet!
Price was more than reasonable too.
We give it 5 Paws Up!
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Reviewed in the United States on May 25, 2026
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